منابع مشابه
Another way to break down
hen yeast secretory proteins are improperly folded, the ER quality control system directs them into the HRD/DER pathway, which targets the proteins for degradation. Blocking the HRD/DER pathway, however, does not completely stop degradation, implying that there must be an alternative way to destroy misfolded secretory proteins. Haynes et al., reporting on page 91, have now characterized that pa...
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Two major types of passive margins are recognized, i.e. volcanic and non-volcanic, without proposing distinctive mechanisms for their formation. Volcanic passive margins are associated with the extrusion and intrusion of large volumes of magma, predominantly mafic, and represent distinctive features of Larges Igneous Provinces, in which regional fissural volcanism predates localized syn-magmati...
متن کاملA way to break supersymmetry
I study the spontaneous breakdown of supersymmetry when higher-dimensional Yang-Mills or the type-I SO(32) string theory are compactified on magnetized tori. Because of the universal gyromagnetic ratio g = 2, the splittings of all multiplets are given by the product of charge times internal helicity operators. As a result such compactifications have two remarkable and robust features: (a) they ...
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Granzyme A (GzmA) is the most abundant serine protease in killer cell cytotoxic granules. GzmA activates a novel programed cell death pathway that begins in the mitochondrion, where cleavage of NDUFS3 in electron transport complex I disrupts mitochondrial metabolism and generates reactive oxygen species (ROS). ROS drives the endoplasmic reticulum-associated SET complex into the nucleus, where i...
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ONE THEME of the NHS Plan is the government's desire for the barriers between thet raditional roles of nurses and doctors to be broken down.
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2002
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1581iti3